Enzymes are an inherent part in modern industries and medicine due to their properties like stability and catalytic activity. The use of enzymes in various industries (e.g. food, agriculture, chemicals, and pharmaceuticals) is increasing rapidly by reason of reducing processing time, lowering energy input, their positive impact of cost effectiveness and because of their nontoxic and eco-friendly characteristics.

We at ARTES develop “ready-to-transfer” cell line and processes for enzymes suitable for large scale manufacturing with low cost-of-goods.

The yeast technology platform Hansenula polymorpha realizes m³ scales at extremely reduced manufacturing costs due to growth and enzyme production is due in fully synthetic media supplemented with nitrogen and carbon sources. These carbon sources can be derived from industrial waste streams (bio-diesel waste, molasse, rape seed extract). Sustainability and cost saving are ideally combined in our innovative solutions!

In accordance with the regulation No. 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition, ARTES applies an antibiotic-resistance free technology platform for production of GRAS confirmed feed and food enzymes.

ARTES offers a range of enzyme producing cell lines and processes for out-licensing and technology transfer. All listed cell lines are based on our safe and high yield yeast expression systems Hansenula polymorpha or E.coli.

NameDonor organismEC number
Phy­taseAspergillus ficuum3.1.3.8
CalB LipaseCandida antarctica3.1.1.3
Endoglu­canase IITrichoderma reesei3.2.1.4
D-Galactose-1-DehydrogenaseXanthomonas campestris1.1.1.48
3-alpha-Hydroxysteroid-DehydrogenasePseudomonas spec.
Cel­lobio­hy­dro­lase ITrichoderma viride3.2.1.91
Cel­lobio­hy­dro­lase IITrichoderma reesei3.2.1.91
Endoglu­canase ITrichoderma reesei3.2.1.4
alpha-MannosidaseAspergillus saitoi3.2.1.113
alpha-AmylaseSchwanniomyces occidentalis3.2.1.1
endo-ß-1,4-XylanasePenicillium simplicissimum3.2.1.8
Endoglycosidase HStreptomyces plicatus3.2.1.96

To obtain a quote, please contact us at info(at)artes-biotechnology.com indicating name of the vaccine of interest to you. We will revert to you with a dedicated offer specifying delivery times and cost.