Enzymes are an integral part of modern industry and medicine due to their properties such as stability and catalytic activity. Their use in various industries (e.g. food, agriculture, chemical, and pharmaceutical) is rapidly increasing due to the reduction of processing time, reduction of energy input, their positive impact on cost effectiveness and because of their non-toxic and eco-friendly characteristics.

We at ARTES develop “ready-to-transfer” cell lines and processes for enzymes suitable for large scale manufacturing at low cost-of-goods.

The yeast technology platform Hansenula polymorpha realizes m³ scales at extremely reduced manufacturing costs due to growth and enzyme production in fully synthetic media supplemented with nitrogen and carbon sources. These carbon sources can be derived from industrial waste streams (biodiesel waste, molasse, rape seed extract). Sustainability and cost savings are ideally combined in our innovative solutions!

In compliance with the Regulation No. 1831/2003 of the European Parliament and of the Council of 22 September 2003 on additives for use in animal nutrition, ARTES applies an antibiotic resistance-free technology platform for the production of GRAS-confirmed feed and food enzymes.

ARTES offers a range of enzyme-producing cell lines and processes for out-licensing and technology transfer. All listed cell lines are based on our safe and high yielding yeast expression systems Hansenula polymorpha or E. coli.

NameDonor organismEC number
Phy­taseAspergillus ficuum3.1.3.8
CalB LipaseCandida antarctica3.1.1.3
Endoglu­canase IITrichoderma reesei3.2.1.4
D-Galactose-1-DehydrogenaseXanthomonas campestris1.1.1.48
3-alpha-Hydroxysteroid-DehydrogenasePseudomonas spec.
Cel­lobio­hy­dro­lase ITrichoderma viride3.2.1.91
Cel­lobio­hy­dro­lase IITrichoderma reesei3.2.1.91
Endoglu­canase ITrichoderma reesei3.2.1.4
alpha-MannosidaseAspergillus saitoi3.2.1.113
alpha-AmylaseSchwanniomyces occidentalis3.2.1.1
endo-ß-1,4-XylanasePenicillium simplicissimum3.2.1.8
Endoglycosidase HStreptomyces plicatus3.2.1.96

We also have a selection of ready-to-use cell lines and processes for vaccines or biosimilars.

To receive a quote, please contact us at info(at)artes-biotechnology.com and indicate the name or EC number of the enzyme you are interested in. We will get back to you with a specific quote including delivery time and cost.