Phar­ma­ceu­ti­cals – Flavours – Fra­grances – Cos­met­ic Ingre­di­ents – Fine Chem­i­cals

Whole-cell cat­a­lysts can act as high­ly spe­cif­ic, reusable tools in the man­u­fac­ture of var­i­ous fine chem­i­cals, phar­ma­ceu­ti­cals, fra­grances and cos­met­ic ingre­di­ents. Con­ver­sion of low cost sub­strate into high val­ue prod­uct can be real­ized in high­ly sus­tain­able process­es. While chem­i­cal reac­tions gen­er­al­ly result in con­se­quences such as pro­duc­tion of waste streams con­tain­ing var­i­ous tox­ic acids and heavy met­als and gen­er­a­tion of unde­sired by-prod­ucts, inno­v­a­tive process­es involv­ing yeast based whole-cell bio­cat­a­lysts gen­er­ate pure prod­uct at high effi­cien­cy and with­out unwant­ed, haz­ardous waste.

With ARTES´ yeast tech­nol­o­gy com­plex biosyn­thet­ic path­ways can be sta­bly imple­ment­ed and reusable bio­cat­a­lysts can be man­u­fac­tured at large scale and low costs.

Exam­ples of Hansenu­la based bio­cat­alyt­ic con­ver­sions:

  • pro­duc­tion of enan­tiomer­ic pure alco­hols (1-S-phenylethanol, …
  • pro­duc­tion of pyru­vic acid and gly­oxylic acid
  • pro­duc­tion of Ectoin resp. Hydroxy-Ectoin as sub­stances in cos­met­ics
  • pro­duc­tion of cell-wall anchored enzymes; e.g. Can­di­da antarc­ti­ca Lipase B (CalB)